Intramolecular Mannich reaction of 2-oxotryptamine and homologues with oxo reagents yielding spiro compounds. Part II

G Dörnyei, M Incze, M Kajtár-Peredy…

文献索引：Doernyei, Gabor; Incze, Maria; Kajtar-Peredy, Maria; Szantay, Csaba Collection of Czechoslovak Chemical Communications, 2002 , vol. 67, # 11 p. 1669 - 1680

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被引用次数: 10

摘要

Abstract 2-Oxotryptamine and its homo derivative undergo intramolecular Mannich-type cyclization with acetone and other ketones to give spiro [indole-3, 3'-pyrrolidin]-2-ones and spiro [indole-3, 3'-piperidin]-2-ones. A similar reaction with the bis-homologue of 2- oxotryptamine to yield spiro [azepane-3, 3'-indol]-2'-ones was unsuccessful.