Chemistry–A European Journal

Substrate??Dependent Stereospecificity of Tyl??KR1: An Isolated Polyketide Synthase Ketoreductase Domain from Streptomyces fradiae

M Häckh, M Müller, S Lüdeke

文献索引：Luedeke, Steffen; Richter, Michael; Mueller, Michael Advanced Synthesis and Catalysis, 2009 , vol. 351, # 1-2 p. 253 - 259

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被引用次数: 10

摘要

Abstract The stereospecificity of an enzymatic reaction depends on the way in which a substrate and its enantiomer bind to the active site. These binding modes cannot be easily predicted. We have studied the stereospecificity and stereoselectivity of the ketoreductase