1. Radiolabelled [35 S]-phenothiazine has been administered orally to two healthy adult male volunteers (6mg kg-1 body weight). Faeces were the major route of excretion of radioactivity (68%), the remainder being eliminated via the urine (32%) with an estimated urinary half-life (biphasic) of 6-16 h. Over the 5 days of the study a complete recovery of radioactivity was achieved. 2. From urinary data, it was shown that metabolism occurred ...
