Synthesis and antitubercular activity of novel Schiff bases derived from D-mannitol
ML Ferreira, TRA Vasconcelos, EM de Carvalho…
文献索引：Ferreira, Marcelle de L.; Vasconcelos, Thatyana R.A.; de Carvalho, Erika M.; Lourenco, Maria C.S.; Wardell, Solange M.S.V.; Wardell, James L.; Ferreira, Vitor F.; de Souza, Marcus V.N. Carbohydrate Research, 2009 , vol. 344, # 15 p. 2042 - 2047
Six Schiff base derivatives of d-mannitol, 1, 6-dideoxy-1, 6-bis-{[(E)-arylmethylidene] amino}- d-mannitol (6: aryl= XC6H4: X= o-, m-and p-Cl or NO2), have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue susceptibility test and the activity expressed as the minimum inhibitory concentration (MIC) in μg/mL. All three nitro derivatives exhibit significant ...
