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Synthesis of fluorescent derivatives of the antibiotic moenomycin A

…, M Findeisen, D Müller, S Giesa, H Knoll…

文献索引:Buchynskyy, Andrij; Kempin, Uwe; Vogel, Stefan; Hennig, Lothar; Findeisen, Matthias; Mueller, Dietrich; Giesa, Sabine; Knoll, Helmut; Welzel, Peter European Journal of Organic Chemistry, 2002 , # 7 p. 1149 - 1162

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被引用次数: 11

摘要

Abstract Moenomycin has been highly selectively converted into amino derivative 3b. The primary amino group of this compound can be used to attach various fluorescent labels to moenomycin, through conversion of isothiocyanates into thioureas and squaric acid diesters into diamides. The application of some of the derivatives is outlined.(© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)