Tetrahedron Letters

Dithio-phospholipids for oriented immobilization of proteins to gold surfaces

G Kada, CK Riener, HJ Gruber

文献索引：Kada, Gerald; Riener, Christian K.; Gruber, Hermann J. Tetrahedron Letters, 2001 , vol. 42, # 14 p. 2677 - 2680

全文：HTML全文

被引用次数: 10

摘要

We report the syntheses of phospholipids containing a dithio-group on their hydrophobic end and a choline or a biotin-group on their hydrophilic end. As demonstrated by surface plasmon resonance, a monolayer of these dithiolipids on gold affords specific binding of streptavidin and of biotinylated molecules in further steps.