Zur Ringumwandlung von 2-Amino-thiophen-3-carbonsäureestern: Pyridon-und Pyridazinon-Derivate

K Gewald, M Gruner, U Hain, G Süptitz

文献索引：Gewald, Karl; Gruner, Margit; Hain, Ute; Sueptitz, Gabriele Monatshefte fuer Chemie, 1988 , vol. 119, p. 985 - 992

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被引用次数: 3

摘要

Abstract Whereas treatment of the ethyl 5-acetyl-2-amino-4-methyl-thiophene-3-carboxylate (1) with potassium hydroxide yields the 2-hydroxy-thiophene-3-carbonitrile 4 its hydrazone 2 is converted into the 1-amino-5-mercapto-2-pyridone derivative 6. The transformation of the 2-amino-5-phenylazo-thiophene derivative 9 by potassium hydroxide yields the substituted 3-mercapto-pyridazin-6 (1 H) one 10, with sodium ethoxide the 5-phenylhydrazono-2-oxo- ...