Tetrahedron letters

Aqueous phase synthesis of thiazoles and aminothiazoles in the presence of β-cyclodextrin

M Narender, MS Reddy, R Sridhar, YVD Nageswar…

文献索引：Narender; Somi Reddy; Sridhar; Nageswar; Rama Rao Tetrahedron Letters, 2005 , vol. 46, # 35 p. 5953 - 5955

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被引用次数: 84

摘要

The thiazole ring system is a useful structural motif found in numerous biologically active molecules. 1 This structure has found applications in drug development for the treatment of allergies, 2 hypertension, 3 schizophrenia, 4 inflammation, 5 bacterial 6 and HIV 7 infections. Aminothiazoles are known to be ligands of estrogen receptors 8 as well as a novel class of adenosine receptor antagonists 9 whereas other analogues are used as ...