Design and synthesis of N-2, 6-difluorophenyl-5-methoxyl-1, 2, 4-triazolo [1, 5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor

CN Chen, LL Lv, FQ Ji, Q Chen, H Xu, CW Niu…

文献索引：Chen, Chao-Nan; Lv, Li-Li; Ji, Feng-Qin; Chen, Qiong; Xu, Hui; Niu, Cong-Wei; Xi, Zhen; Yang, Guang-Fu Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 8 p. 3011 - 3017

全文：HTML全文

被引用次数: 42

摘要

Triazolopyrimidine-2-sulfonamide belongs to a herbicide group called acetohydroxyacid synthase inhibitors. With the aim to discover new triazolopyrimidine sulfonanilide compounds with high herbicidal activity and faster degradation rate in soil, the methyl group of Flumetsulam (FS) was modified into a methoxy group to produce a new herbicidal compound, N-2, 6-difluorophenyl-5-methoxy-1, 2, 4-triazolo [1, 5-a] pyrimidine-2- ...