Preparation of (R)-(−)-and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors
... Tetrahedron: Asymmetry. Volume 14, Issue 3, 7 February 2003, Pages 381–387. ... Due to the asymmetry of bioactive macromolecules including enzymes, G-protein coupled receptors, ion-channels and nucleic acids, the binding of chiral ligands and substrates proceeds ...
