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Tetrahedron: Asymmetry

Preparation of (R)-(−)-and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors

Y Caro, CF Masaguer, E Raviña

文献索引:Tetrahedron Asymmetry, , vol. 14, # 3 p. 381 - 387

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被引用次数: 19

摘要

... Tetrahedron: Asymmetry. Volume 14, Issue 3, 7 February 2003, Pages 381–387. ... Due to the asymmetry of bioactive macromolecules including enzymes, G-protein coupled receptors, ion-channels and nucleic acids, the binding of chiral ligands and substrates proceeds ...