Synthesis of new (benzimidazolyl) piperazines with affinity for the 5-HT 1A receptor via Pd (0) amination of bromobenzimidazoles

ML López-Rodríguez, A Viso, B Benhamú…

文献索引：Lopez-Rodriguez, Maria L.; Viso, Alma; Benhamu, Bellinda; Rominguera, J. Luis; Murcia, Marta Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2339 - 2342

全文：HTML全文

被引用次数: 15

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis of a new family of (benzimidazolyl)piperazines has been developed through Pd(0) mediated amination of 4- and 6-bromobenzimidazole derivatives. Preliminary studies showed that some of these compounds are potent 5-HT 1A receptor ligands.