Tetrahedron letters

Synthesis of 2, 3, 5-substituted pyrrole derivatives

PMT Ferreira, HLS Maia, LS Monteiro

文献索引：Ferreira, Paula M.T.; Maia, Hernani L.S.; Monteiro, Luis S. Tetrahedron Letters, 2002 , vol. 43, # 25 p. 4491 - 4493

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被引用次数: 24

摘要

2, 3, 5-Substituted pyrrole derivatives are prepared by treatment of 2, 3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the β-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tert-butyloxycarbonyl)- dehydroalanine methyl ester.