Bioorganic & medicinal chemistry letters

Synthesis, antioxidant, and antimicrobial evaluation of some 2-arylbenzimidazole derivatives

B Zhou, B Li, W Yi, X Bu, L Ma

文献索引：Zhou, Binhua; Li, Baojian; Yi, Wei; Bu, Xianzhang; Ma, Lin Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3759 - 3763

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被引用次数: 18

摘要

A series of 2-arylbenzimidazole derivatives (3a–3p and 4a–4i) were synthesized and evaluated as potential antioxidant and antimicrobial agents. Their antioxidant properties were evaluated by various in vitro assays including hydroxyl radical (HO) scavenging, superoxide radical anion (O2−) scavenging, 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and ferric reducing antioxidant power. Results demonstrated that compounds ...