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Journal of Heterocyclic Chemistry

The synthesis and chemical reactivity of thieno [2, 3??c]??and thieno [3, 2??c] pyridines

ML Dressler, MM Joullié

文献索引:Dressler,M.L.; Joullie,M.M. Journal of Heterocyclic Chemistry, 1970 , vol. 7, p. 1257 - 1268

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被引用次数: 10

摘要

Abstract The syntheses and reactions of various thieno [2, 3-c]-and thieno [3, 2-c] pyridines are described. Molecular orbital calculations were performed on thieno [2, 3-c] pyridine (1) in order to determine the most susceptible sites to electrophilic and nucleophilic attack. Superdelocalizability values, S r-are reported for each position in this molecule to give relative orders of reactivity towards the two types of reactions. Electrophilic attack was ...