Tetrahedron letters

Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity

JC Trivedi, JB Bariwal, KD Upadhyay, YT Naliapara…

文献索引：Trivedi, Jalpa C.; Bariwal, Jitender B.; Upadhyay, Kuldip D.; Naliapara, Yogesh T.; Joshi, Sudhir K.; Pannecouque, Christophe C.; De Clercq, Erik; Shah, Anamik K. Tetrahedron Letters, 2007 , vol. 48, # 48 p. 8472 - 8474

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被引用次数: 95

摘要

Two closely structurally related coumarins, 4-hydroxy-8-isopropyl-5-methylcoumarin and 4- hydroxy-6-chloro-7-methylcoumarin were acylated at C-3 and further converted to the respective chalcones and two series of eighteen new compounds, which were evaluated for possible antiviral activity.