Synthetic Communications®

Convenient Synthesis of N-Hydroxysuccinimide Esters from Carboxylic Acids Using Triphosgene

M Kim, KJ Han

文献索引：Kim, Misoo; Han, Ki-Jong Synthetic Communications, 2009 , vol. 39, # 24 p. 4467 - 4472

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被引用次数: 7

摘要

Abstract A simple and convenient method for the synthesis of N-hydroxysuccinimide ester is developed using triphosgene as an acid activator. Several aromatic and aliphatic N- hydroxysuccinimide esters are prepared from their corresponding carboxylic acids at room