… one or two chiral auxiliaries. Asymmetric reduction of methyl benzoylformate and N-acetyl-enamines. Influence of the magnesium salt concentration on the asymmetric …

C Leroy, V Levacher, G Dupas, G Quéguiner…

文献索引：Leroy, Corine; Levacher, Vincent; Dupas, Georges; Queguiner, Guy; Bourguignon, Jean Tetrahedron Asymmetry, 1997 , vol. 8, # 19 p. 3309 - 3318

全文：HTML全文

被引用次数: 11

摘要

The synthesis of NADH models in the pyrrolo [2, 3-b] pyridine series bearing one or two chiral auxiliaries either at the pyridine or at the pyrrole ring is described. These models were involved in the reduction of methyl benzoylformate. The reactivity of these reagents and the stereochemical outcome of reductions are discussed in relation to the nature of the chiral auxiliary at the pyrrole ring and the magnesium ions concentration. Reagent 3 showed an ...