Tetrahedron

Total syntheses of the lignans isolated from Schisandra chinensis

…, T Ohshima, H Mitsuhashi, M Maruno, T Wakamatsu

文献索引：Tanaka, Masahide; Ohshima, Toshihiro; Mitsuhashi, Hiroshi; Maruno, Masao; Wakamatsu, Takeshi Tetrahedron, 1995 , vol. 51, # 43 p. 11693 - 11702

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被引用次数: 30

摘要

The total syntheses of wuweizisu C (4), gomisin J (6), gomisin N (7), and γ-schizandrin (8) having natural configuration were accomplished in a stereoselective manner. The catalytic hydrogenation or the metal mediated 1, 4-reduction of the tetracyclic lactones (12, 17, 22, 30) played the significant role for the stereoselective introduction of C6, C7 dimethyl moiety. Furthermore, the neighboring carbonyl group assisted regioselective demethylation of 5 ...