Straightforward Access to (Imidazol??2??yl) acetates by Reaction of 2??Unsubstituted Imidazole 3??Oxides with Dimethyl Acetylenedicarboxylate

…, M Jasiński, H Heimgartner

文献索引：Mloston, Grzegorz; Jasinski, Marcin; Heimgartner, Heinz European Journal of Organic Chemistry, 2011 , # 13 p. 2542 - 2547

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被引用次数: 5

摘要

Abstract A new method for the preparation of 1, 4, 5-trisubstituted (imidazol-2-yl) acetates, based on the reaction of the corresponding imidazole 3-oxides with dimethyl acetylenedicarboxylate (DMAD) is described. Formation of the products is rationalized by a formal 1, 3-dipolar cycloaddition and subsequent oxaloyl cleavage.