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Journal of fluorine chemistry

New strategies in the synthesis of regioselectively trifluoromethyl-and trifluoromethoxy-substituted arenes as building blocks for biologically active molecules

S Leconte, R Ruzziconi

文献索引:Leconte, Stephane; Ruzziconi, Renzo Journal of Fluorine Chemistry, 2002 , vol. 117, # 2 p. 167 - 172

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被引用次数: 9

摘要

Regioisomerically pure trifluoromethyl-and trifluoromethoxy-substituted aromatic and heteroaromatic aldehydes and carboxylic acids are valuable building blocks for the synthesis of biologically active molecules. They have been prepared by employing modern organometallic methods. On this basis, a novel access to 2, 3-dihydro-5-(trifluoromethoxy) indole was developed which represents an intriguing example of how organometallic and ...