CuH??Catalyzed Asymmetric Conjugate Reductions of Acyclic Enones

BH Lipshutz, JM Servesko

文献索引：Lipshutz, Bruce H.; Servesko, Jeff M. Angewandte Chemie - International Edition, 2003 , vol. 42, # 39 p. 4789 - 4792

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被引用次数: 122

摘要

Strategies for controlling absolute stereochemistry at a site β to an electrophilic center, in particular a ketone, usually rely on organometallic-based Michael additions (Scheme 1, path A).[1] Processes that are catalytic in both the transition metal (M) and the associated nonracemic ligand (L*) are most desirable, and outstanding progress continues to be made with several different Michael donors [1, 2] and acceptors.[1, 3] Acyclic enones have ...