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Synthesis of (3'R, 5'S)-trans-3'-hydroxycotinine, a major metabolite of nicotine. Metabolic formation of 3'-hydroxycotinine in humans is highly stereoselective

P Jacob III, AT Shulgin, NL Benowitz

文献索引:Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1888 - 1891

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被引用次数: 23

摘要

... Address correspondence to Peyton Jacob, 111, Ph.D., San Francisco General Hospital Medical Center, Building 100, Room 235, 1001 Potrero Ave., San Francisco, CA 94110. UO22-2623/90/ 1833-1888$02.50/0 ... Journal of Medicinal Chemistry, 1990, Vol. 33, No. ...