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Synthesis of bisaramil labelled with carbon??14 and deuterium

J Szammer, E Simon??Trompler…

文献索引:Szammer; Simon-Trompler; Mlinko Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 4 p. 313 - 321

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被引用次数: 6

摘要

Abstract [6, 8-14 C 2]-Bisaramil: 3-methyl-7-ethyl-9α-(4-chlorobenzoyloxy)-3, 7- diazabicyclo/3.3. 1./nonane-[6, 8-14 C 2] monohydrochloride and [7-ND 5-ethyl]-Bisaramil: 3- methyl-7-[D 5-ethyl]-9α-(4-chlorobenzoyloxy)-3, 7-diazabicyclo/3.3. 1./nonane monohydrochloride were synthesized in four steps from 14 CO 2 (6% overall yield) and in six steps from [D 6]-ethanol (4% overall yield), respectively.