Abstract By means of regioselective S-alkylation of 1H-1, 2, 4-triazole-3-thiol (1), a series of S-substituted derivatives 2a-j were synthesized. In certain conditions, the reaction of 2 with arylsulfochlorides, arylisocyanates, and quaternary ammonium salts of azines corresponding compounds were obtained 1-arylsulfonyl-(3a-d), 1-arylcarbonamido-(4a, b), and 1-azinyl-1, 2, 4-(6a-p) triazoles. Structures of compounds were confirmed by 1 H NMR ...