Microbial reduction of ω-bromoacetophenones in the presence of surfactants

…, RL Bezbaruah, J Goswami, N Borthakur, D Dey…

文献索引：Goswami; Bezbaruah; Borthakur; Dey; Hazarika Tetrahedron Asymmetry, 2000 , vol. 11, # 18 p. 3701 - 3709

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被引用次数: 34

摘要

Several ω-bromoacetophenone derivatives 6a–f were reduced to (R)-(−)-2-bromo-1- (phenyl/substituted phenyl) ethanol derivatives 7a–f with whole cell biocatalysts in good yields. The enantiomeric excesses were increased to 95% using an anionic surfactant under an inert atmosphere in an aqueous medium.