European Journal of Organic Chemistry

Syntheses of 3??C??methylceramides

P Sawatzki, T Kolter

文献索引：Sawatzki, Peter; Kolter, Thomas European Journal of Organic Chemistry, 2004 , # 17 p. 3693 - 3700

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被引用次数: 8

摘要

Ceramide (N-acylsphingosine 1, Scheme 1) is the hydrophobic membrane anchor of mammalian glycosphingolipids and a vital component of the human skin.1 In addition, ceramide attracted attention as a signaling substance that has been implicated in a variety of biological processes.2,3 In living cells, it usually occurs in low concentrations as an intermediate in sphingolipid- and glycosphingolipid metabolism, and, in higher concentrations, in the ...