The remarkable medical importance and the scarcity in nature of polyphenolic stilbenes prompted studies for their synthesis. The protocols for establishing ethene bridge between the two phenyl rings are mainly associated with diverse reactions, such as the Wittig reaction, [ 10 10. Pettit , GR ; Singh , SB ; Boyd , MR ; Hamel , E. ; Pettit , RK ; Schmidt , JM ; Hogan , F. Antineoplastic agents, 291: Isolation and synthesis of combretastatins A-4, A-5, and A-6 . J. Med. Chem. ...
