Piperidine carboxylic acid derivatives of 10H-pyrazino [2, 3-b][1, 4] benzothiazine as orally-active adhesion molecule inhibitors

T Kaneko, RSJ Clark, N Ohi, F Ozaki…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 52, # 6 p. 675 - 687

被引用次数: 7

摘要

... Chemistry We first prepared the right moieties of the compounds 2. The piperidine carboxylates 4a—c are either commercially ... 2004 Pharmaceutical Society of ... resonance (1H-NMR) spectra were recorded on a Varian Unity 400 (400 MHz) spectrometer, and chemical shifts are ...

159635-49-1

N-Boc-4-亚甲基哌啶

203661-69-2

2-氧代-7-氮杂螺[3.5]...

Discovery of Spirofused Piperazine and Diazepane Amides as S...

[Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758]