Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl) benzoxazole derivatives

H López-Ruiz, H Briseño-Ortega, S Rojas-Lima…

文献索引：Lopez-Ruiz, Heraclio; Briseno-Ortega, Horacio; Rojas-Lima, Susana; Santillan, Rosa; Farfan, Norberto Tetrahedron Letters, 2011 , vol. 52, # 33 p. 4308 - 4312

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被引用次数: 16

摘要

A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2- hydroxyphenyl) benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.