Tetrahedron Letters

Remarkable catalytic activity of silica nanoparticle in the bis-Michael addition of active methylene compounds to conjugated alkenes

S Banerjee, S Santra

文献索引：Banerjee, Subhash; Santra, Swadeshmukul Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2037 - 2040

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被引用次数: 49

摘要

We have demonstrated the remarkable catalytic activity of silica nanoparticles (NPs) in the unusual bis-Michael addition of active methylene compounds to conjugated alkenes at room temperature. The catalyst silica NPs were reused up to seven runs without appreciable loss of catalytic activity.