Tetrahedron letters

Organocatalytic enantioselective Michael addition of thioacetic acid to enones

H Li, L Zu, J Wang, W Wang

文献索引：Li, Hao; Zu, Liansuo; Wang, Jian; Wang, Wei Tetrahedron Letters, 2006 , vol. 47, # 18 p. 3145 - 3148

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被引用次数: 63

摘要

The preparation of sulfur-containing molecules has long been a mainstay of organic synthesis as a result of their broad application to organic and medicinal chemistry. 1 Conjugate addition of sulfur-centered nucleophiles to α,β-unsaturated carbonyls serves as a powerful synthetic method in this area of sulfur chemistry. 2, 3, 4 and 5 While an asymmetric version of this Michael addition process would furnish enantiomerically enriched adducts, to date reports of this reaction ...