Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2', 3'-unsaturated, and 2', 3'-dideoxy analogs of pyrimidine deoxyribonucleosides against retroviruses
…, C McLaren, YS Gao, I Ghazzouli…
文献索引：Lin; Chen; McLaren; Gao; Ghazzouli; Prusoff Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 440 - 444
Various 3'-azido, 3'-amino, 2', 3'-unsaturated, 2', 3'-dideoxy, and 5-substituted analogues of pyrimidine deoxyribonucleosides have been prepared and tested against Moloney-murine leukemia virus (M-MULV), a mammalian T-lymphotropic retrovirus in vitro. Among these compounds, the 3'-azido analogues of thymidine, 2 '-deoxy-5-bromouridine, and 2'-deoxy-5- iodouridine, the 2', 3'-unsaturated analogue of thymidine and 2'-deoxycytidine, and 2', 3'- ...
