Tetrahedron

Oxidation reactions of 2′-functionalized 3-aryltetrahydro and 3, 4-dihydroisoquinolines

N Sotomayor, E Domínguez, E Lete

文献索引：Sotomayor, Nuria; Dominguez, Esther; Lete, Esther Tetrahedron, 1995 , vol. 51, # 46 p. 12721 - 12730

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被引用次数: 25

摘要

Several 2′-functionalized 3-arylisoquinolines in different oxidation stages have been prepared. Fremy's salt or I2/NaAcO oxidation of 2′-functionalized 3- aryltetrahydroisociuinolines always stops at the 3, 4-dihydroisquinoline stage; however, better yields and shorter reaction times are obtained with iodine. Air/KOH/DMSO oxidation of 3, 4-dihydroisoquinolines furnished the aromatic derivatives with concomitant cleavage of ...