Organic letters

Heteroaryl ethers by oxidative palladium catalysis of pyridotriazol-1-yloxy pyrimidines with arylboronic acids

S Bardhan, S Wacharasindhu, ZK Wan…

文献索引：Wacharasindhu, Sumrit; Bardhan, Sujata; Wan, Zhao-Kui; Tabei, Keiko; Mansour, Tarek S. Journal of the American Chemical Society, 2009 , vol. 131, p. 4174 - 4175

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被引用次数: 5

摘要

The oxidative palladium-catalyzed cross-coupling of pyrimidines containing pyridotriazol-1- yloxy (O Pt) as either a urea or an amide functional group with arylboronic acids in the presence of Cs2CO3 in DME containing 0.6− 1.0% H2O is described for the preparation of heteroaryl ethers. The bromo substitution in the case of 3-(5-bromo-pyrimidin-2-yloxy)-3 H- [1, 2, 3] triazolo [4, 5-b] pyridine 1 could serve as a handle for further elaborations such as ...