Journal of the American Chemical Society

On the mechanism of thiamine action. IV. 1 Evidence from studies on model systems

R Breslow

文献索引：Breslow Journal of the American Chemical Society, 1958 , vol. 80, p. 3719,3725

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被引用次数: 1315

摘要

Thiamine (Ia), in the form of its pyrophosphate, cocarboxylase (Ib), is the coenzyme for a number of important biochemical reactions, including the decarboxylation of pyruvic acid to acetaldehyde, the conversion of pyruvic acid to acetoin and the transketolase reaction; it is also involved in the oxidative decarboxylation of pyruvic acid to “active acetate.''