The Journal of Organic Chemistry

Reagents for the stepwise functionalization of spermine

RJ Bergeron, JS McManis

文献索引：Bergeron, R. J.; McManis, J. S. Journal of Organic Chemistry, 1988 , vol. 53, # 13 p. 3108 - 3111

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被引用次数: 94

摘要

In recent years, there has been growing interest in the polyamines putrescine, spermidine, and spermine. These amines are widespread in nature and are implicated in the control of proliferative This latter role is largely responsible for the recent surge in the synthesis of polyamine derived compounds. We have, in recent years, synthesized a number of polyamine analogues which have demonstrated potent antineoplastic activity4 and have ...