Syntheses and Applications of Monofluorinated Cyclopropanes

…, P Ivashkin, S Couve??Bonnaire…

文献索引：Ivashkin, Pavel; Couve-Bonnaire, Samuel; Jubault, Philippe; Pannecoucke, Xavier Organic Letters, 2012 , vol. 14, # 9 p. 2270 - 2273

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被引用次数: 1

摘要

Abstract The combination of a fluorine atom and a cyclopropane ring, which both possess unique structural and chemical features, can generate new relevant building blocks for the discovery of efficient fluorinated biologically active agents. In this review, we report the different strategies to access monofluorocyclopropanes and highlight some of their attractive biological applications.