Convenient synthesis of some 2??substituted 4 (3H)??quinazolinone derivatives

I Philipova, G Dobrikov, K Krumova…

文献索引：Philipova; Dobrikov; Krumova; Kaneti Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 1057 - 1063

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被引用次数: 23

摘要

4 (3H)-Quinazolinones 1 are known for more than a century [1]. Molecules based on quinazoline and quinazolinone exhibit a multitude of interesting pharmacological activities [2], including anticonvulsant, antibacterial and antidiabetic activity [3, 4]. The important natural and synthetic 4 (3H)-quinazolinones include l-vasicinone 2 [5], chrysogine 3 [6], methaquinalon 4 [7]–a sedative, piriqualone 5 [8, 9]–an anticonvulsant, although the latter ...