Abstract The preparation of some novel fluorodeoxy nucleosides in good yields by the fluorination of unsaturated intact nucleosides with elemental fluorine at− 78 C in mixtures of chloroform, ethanol and fluorotrichloromethane is described. This is the first example of the fluorination of an intact nucleoside by elemental fluorine and represents a considerable step forward in the use of the element in the synthesis of bioactive species. Thus, we were able ...
