Ferrocenyl chalcones versus organic chalcones: A comparative study of their nematocidal activity

…, H Alhaddad, ML Golden, A Calderón-Urrea

文献索引：Attar, Saeed; O'Brien, Zachary; Alhaddad, Hasan; Golden, Melissa L.; Calderon-Urrea, Alejandro Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2055 - 2073

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被引用次数: 41

摘要

A series of 30 organic chlacones and 33 ferrocenyl (Fc) chalcones were synthesized and characterized by melting point, elemental analysis, spectroscopy (1H NMR and FTIR) and, in two cases, by X-ray crystallography. The biological activity of each compound (10− 4M in DMSO) against the model nematode Caenorhabditis elegans was examined in terms of% mortality (percent nematodes that died) and% fecundity (percent nematodes that ...