Synthesis, characterization, antitumor, and cytotoxic activity of mononuclear Ru (II) complexes

…, KN Jayaveera, J Balzarini, ED Clercq

文献索引：Thota, Sreekanth; Karki, Subhas Somalingappa; Jayaveera; Balzarini, Jan; Clercq, Erik De Journal of Coordination Chemistry, 2010 , vol. 63, # 24 p. 4332 - 4346

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被引用次数: 8

摘要

In the search for antitumor active metal complexes several ruthenium complexes have been reported to be promising. A series of mononuclear Ru (II) complexes,[Ru (T) 2 (S)] 2+, where T= 2, 2′-bipyridine/1, 10-phenanthroline and S= CH3-bitsz, Cl-bitsz, Br-bitsz, tmtsz, dmtsz, have been prepared and characterized by UV-Vis, IR, 1H-NMR, FAB-mass spectroscopy, and elemental analysis. The complexes were subjected to in vivo anticancer activity ...