Tetrahedron

Cu (OTf) 2-catalyzed arylmethylation of terminal alkynes with benzylic alcohols under ligand-, base-, and additive-free reaction conditions

K Ren, P Li, L Wang, X Zhang

文献索引：Ren, Kai; Li, Pinhua; Wang, Lei; Zhang, Xiuli Tetrahedron, 2011 , vol. 67, # 15 p. 2753 - 2759

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被引用次数: 19

摘要

An effective, convenient, and mild coupling reaction of benzylic alcohols with terminal alkynes has been developed. As an effective Lewis acid, Cu (OTf) 2-catalyzed arylmethylation of terminal alkynes with benzylic alcohols generated the corresponding products in BrCH2CH2Br with good yields in the absence of ligand, base, and additive.