Il Farmaco

Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue

…, D Szymanowicz, H Kusnierczyk, J Wietrzyk, A Opolski

文献索引：Misiura, Konrad; Szymanowicz, Daria; Kusnierczyk, Halina; Wietrzyk, Joanna; Opolski, Adam Farmaco, 2002 , vol. 57, # 4 p. 315 - 319

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被引用次数: 6

摘要

Racemic mixtures and laevorotatory enantiomers of cis-and trans-4-hydroperoxyifosfamide and 4-hydroperoxybromofosfamide possess high antitumour activity both in vitro and in vivo. However, no major differences in biological activity were observed among these stereoisomers.