Synthesis and biological properties of 4-(3H)-quinazolone derivatives

…, A Bajpai, G Shukla, S Singh, AK Mishra

文献索引：Tiwari, Anjani K.; Singh, Vinay Kumar; Bajpai, Aruna; Shukla, Gauri; Singh, Sweta; Mishra, Anil K. European Journal of Medicinal Chemistry, 2007 , vol. 42, # 9 p. 1234 - 1238

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被引用次数: 46

摘要

A new quinazolone series has been designed, and synthesized by the anthranilic acid and different acid derivatives. Their structures have been elucidated on the basis of elemental analyses and spectral studies (IR, 1H NMR, FT-IR and FAB-MS). A preliminary radiolabelling study with technetium has shown a very good future prospect for further evaluation in vivo. The biological activities (antifungal, antibacterial as well as ...