Regiocontrolled Hydroarylation of (Trifluoromethyl) acetylenes in Superacids: Synthesis of CF3??Substituted 1, 1??Diarylethenes
…, VM Muzalevskiy, AV Vasilyev, GK Fukin…
文献索引：Alkhafaji, Haider M. H.; Ryabukhin, Dmitry S.; Muzalevskiy, Vasiliy M.; Vasilyev, Aleksander V.; Fukin, Georgy K.; Shastin, Alexey V.; Nenajdenko, Valentine G. European Journal of Organic Chemistry, 2013 , # 6 p. 1132 - 1143
Abstract The reactions between aryl (trifluoromethyl)-substituted alkynes and arenes in triflic and fluorosulfonic acids were investigated. These reactions proceeded 100% regioselectively to give 1, 1-diaryl-2-trifluoromethylethenes in high yields. Depending on the workup conditions, 3, 3, 3-trifluoro-1, 1-diarylpropan-1-ol was also detected in the product mixture. The reaction mechanism was studied by both spectroscopic and theoretical ...
