Efficient and Simple Route for the Synthesis of N-(2-Pyridyl)-4-ethoxy-5-oxo-2, 5-dihydro-1 H-pyrrole-2, 3-dicarboxylates

M Anary-Abbasinejad, M Mirhossaini…

文献索引：Anary-Abbasinejad, Mohammad; Mirhossaini, Marzieh; Parhami, Azadeh; Pourhassan, Ehsanorreza Synthetic Communications, 2010 , vol. 40, # 9 p. 1350 - 1359

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被引用次数: 3

摘要

Three-component reaction of 2-aminopyridines, dialkyl acetylenedicarboxylates, triphenylphosphine, and ethyl chlorooxoacetate in the presence of triethylamine provides a sufficient route for the synthesis of dialkyl N-(2-pyridyl)-4-ethoxy-5-oxo-2, 5-dihydro-1 H- pyrrole-2, 3-dicarboxylates in good yields.