Synthesis of α??Amino Acids by Umpolung of Weinreb Amide Enolates

S Hirner, DK Kirchner, P Somfai

文献索引：Hirner, Sebastian; Kirchner, Donata K.; Somfai, Peter European Journal of Organic Chemistry, 2008 , # 33 p. 5583 - 5589

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被引用次数: 9

摘要

Abstract An efficient and diastereoselective synthesis of α-amino acids from readily available starting materials has been developed. The key feature of this reaction is an umpolung of a glycine-derived enolate, providing an alternative approach for the synthesis of α-amino acids.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)