Molecules

A Facile One-pot Synthesis of 1-Arylpyrazolo [3, 4-d] pyrimidin-4-ones

X Zhang, Q Lin, P Zhong

文献索引：Zhang, Xiaohong; Lin, Qiulian; Zhong, Ping Molecules, 2010 , vol. 15, # 5 p. 3079 - 3086

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被引用次数: 14

摘要

Abstract One pot synthesis of 1-arylpyrazolo [3, 4-d] pyrimidin-4-ones by the reaction of 5- amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl 3 has been developed. The structures of all the title compounds have been confirmed by IR, 1 H-NMR, 13C-NMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction ...