Antiinflammatory Properties of 8-Aryl-5-isopropyl-2H-1, 3-dioxolo [4, 5-g] quinazolin-6 (5H)-ones and-thiones
…, R Van Bochoven, J Perrine, EI Takesue…
文献索引：Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113
A series of 8-aryl-5-isopropyl-2H-1, 3-dioxolo [4, 5-g] quinazolin-6 (5H)-ones and-thiones was prepared and evaluated for antiinflammatory activity. The &phenyl-, 8-(3-fluorophenyl)-, and 8-(4-fluorophenyl)-2H-1, 3-dioxolo [4, 5-g]-quinazolin-6 (5H)-ones and the 8-phenyl-2H- l, 3-dioxolo [4, 5-g] quinazolin-6 (5H)-thione were found to exhibit activity in the range of indomethacin and proquazone.
