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Organic letters

Convergent Synthesis of Fully Functionalized Ring C Allocolchicinoids. Benzannulation Approach

AV Vorogushin, WD Wulff, HJ Hansen

文献索引:Vorogushin, Andrei V.; Wulff, William D.; Hansen, Hans-JUrgen Organic Letters, 2001 , vol. 3, # 17 p. 2641 - 2644

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被引用次数: 24

摘要

A novel convergent approach to fully functionalized ring C allocolchicinoids is developed which is based on the benzannulation reaction of Fischer carbene complexes with alkynes. The efficacy of this strategy was established with the conversion of bromide 1a (R1= Me, ...